Synthesis and pharmacological characterization of l-trans-4-tetrazolylproline (ly300020): A novel systemically-active ampa receptor agonist
- 1 January 1993
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 3 (1) , 95-98
- https://doi.org/10.1016/s0960-894x(00)80099-2
Abstract
No abstract availableKeywords
This publication has 19 references indexed in Scilit:
- The revenge of the kainate receptorTrends in Neurosciences, 1991
- Excitatory amino acids: new tools for old stories or Pharmacological subtypes of glutamate receptors: electrophysiological studiesCanadian Journal of Physiology and Pharmacology, 1991
- Conformationally defined neurotransmitter analogs. Selective inhibition of glutamate uptake by one pyrrolidine-2,4-dicarboxylate diastereomerJournal of Medicinal Chemistry, 1991
- 4-(Tetrazolylalkyl)piperidine-2-carboxylic acids. Potent and selective N-methyl-D-aspartic acid receptor antagonists with a short duration of actionJournal of Medicinal Chemistry, 1991
- Synthesis and activity of a potent N-methyl-D-aspartic acid agonist, trans-1-aminocyclobutane-1,3-dicarboxylic acid, and related phosphonic and carboxylic acidsJournal of Medicinal Chemistry, 1990
- Synthesis and bioactivity of a new class of rigid glutamate analogs. Modulators of the N-methyl-D-aspartate receptorJournal of Medicinal Chemistry, 1990
- A unified approach to systematic isosteric substitution for acidic groups and application to NMDA antagonists related to 2-amino-7-phosphonoheptanoateJournal of Medicinal Chemistry, 1990
- Dinucleotide analogs as inhibitors of thymidine kinase, thymidylate kinase and ribonucleotide reductaseJournal of Medicinal Chemistry, 1988
- Synthesis and pharmacological activity of angiotensin-converting enzyme inhibitors: N-(mercaptoacyl)-4-substituted-(S)-prolinesJournal of Medicinal Chemistry, 1988
- BINDING OF [3H]KAINIC ACID, AN ANALOGUE OF l‐GLUTAMATE, TO BRAIN MEMBRANESJournal of Neurochemistry, 1976