Scalloped Pupils in Familial Amyloidosis

Abstract
THE purpose of this report is to call attention to a pupillary sign of dominantly inherited amyloidosis. We encountered the sign, reported in 1952 by Andrade,1 in one of two brothers who were already known to have amyloidosis. Its presence in a woman with peripheral neuropathy correctly led us to the diagnosis of amyloidosis.Case ReportsCase 1. A 44-year-old man from a large kinship with a dominantly inherited disorder characterized by peripheral neuropathy and nephropathy had a progressive peripheral polyneuropathy. Amyloid was found on sural-nerve and kidney biopsies. He had opacities of the vitreous of both eyes. The right . . .

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