Evidence for Position-Effect Suppression of the Ribosomal RNA Cistrons in Drosophila melanogaster
- 1 October 1971
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 68 (10) , 2472-2476
- https://doi.org/10.1073/pnas.68.10.2472
Abstract
Unambiguous evidence is presented that two X-chromosome inversions produce lethality in X/O males because of position-effect suppression of genes in the basal heterochromatin. The data support the hypothesis that the ribosomal RNA cistrons are the genes suppressed. There is evidence for a region in the X basal heterochromatin that may act as a regulator of rDNA activity.Keywords
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