Botulinum and tetanus neurotoxins: structure, function and therapeutic utility
Top Cited Papers
- 1 November 2002
- journal article
- review article
- Published by Elsevier in Trends in Biochemical Sciences
- Vol. 27 (11) , 552-558
- https://doi.org/10.1016/s0968-0004(02)02177-1
Abstract
No abstract availableKeywords
This publication has 61 references indexed in Scilit:
- High Sensitivity of Mouse Neuronal Cells to Tetanus Toxin Requires a GPI-Anchored ProteinBiochemical and Biophysical Research Communications, 2001
- Site-Directed Mutagenesis Identifies Active-Site Residues of the Light Chain of Botulinum Neurotoxin Type ABiochemical and Biophysical Research Communications, 2001
- Structure‐based sequence alignment for the β‐trefoil subdomain of the clostridial neurotoxin family provides residue level information about the putative ganglioside binding siteFEBS Letters, 2000
- Regular review: Uses of botulinum toxin injection in medicine todayBMJ, 2000
- Sequence homology and structural analysis of the clostridial neurotoxinsJournal of Molecular Biology, 1999
- The high‐affinity binding of Clostridium botulinum type B neurotoxin to synaptotagmin II associated with gangliosides GT1b/GD1aFEBS Letters, 1996
- Expression and Purification of the Light Chain of Botulinum Neurotoxin A: A Single Mutation Abolishes Its Cleavage of SNAP-25 and Neurotoxicity after Reconstitution with the Heavy ChainBiochemistry, 1995
- SNARE motif and neurotoxinsNature, 1994
- Bacterial protein toxins penetrate cells via a four‐step mechanismFEBS Letters, 1994
- The N‐terminal half of the heavy chain of botulinum type A neurotoxin forms channels in planar phospholipid bilayersFEBS Letters, 1987