Palindromic repetitive DNA elements with coding potential in Methanocaldococcus jannaschii
- 12 September 2005
- journal article
- research article
- Published by Wiley in FEBS Letters
- Vol. 579 (24) , 5281-5286
- https://doi.org/10.1016/j.febslet.2005.08.051
Abstract
We have identified 141 novel palindromic repetitive elements in the genome of euryarchaeon Methanocaldococcus jannaschii. The total length of these elements is 14.3 kb, which corresponds to 0.9%, of the total genomic sequence and 6.3% of all extragenic regions. The elements can be divided into three groups (MJRE1-3) based on the sequence similarity. The low sequence identity within each of the groups suggests rather old origin of these elements in M. jannaschii. Three MJRE2 elements were located within the protein coding regions without disrupting the coding potential of the host genes, indicating that insertion of repeats might be a widespread mechanism to enhance sequence diversity in coding regions. (c) 2005 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.Keywords
This publication has 32 references indexed in Scilit:
- Discovery of protein-coding palindromic repeats in WolbachiaTrends in Microbiology, 2005
- Shuffling of Sulfolobus genomes by autonomous and non-autonomous mobile elementsBiochemical Society Transactions, 2004
- The insertion of palindromic repeats in the evolution of proteinsTrends in Biochemical Sciences, 2003
- Protein Coding Palindromes Are a Unique but Recurrent Feature in RickettsiaGenome Research, 2002
- Mobile elements in archaeal genomesFEMS Microbiology Letters, 2002
- Transcription attenuation associated with bacterial repetitive extragenic BIME elements 1 1Edited by I. B. HollandJournal of Molecular Biology, 2001
- Non-autonomous mobile elements in the crenarchaeon Sulfolobus solfataricusJournal of Molecular Biology, 2001
- Initial sequencing and analysis of the human genomeNature, 2001
- Gapped BLAST and PSI-BLAST: a new generation of protein database search programsNucleic Acids Research, 1997
- A novel intercistronic regulatory element of prokaryotic operonsNature, 1982