Interspecies comparisons of plasma half‐life of trimethoprim in relation to body mass
- 1 February 1997
- journal article
- research article
- Published by Wiley in Journal of Veterinary Pharmacology and Therapeutics
- Vol. 20 (1) , 48-53
- https://doi.org/10.1046/j.1365-2885.1997.00042.x
Abstract
The relationship between body mass and plasma half‐life of trimethoprim was studied in 10 different species of animals and man using published data. Log half‐life was positively and significantly correlated to log body mass based on individual measurements in herbivorous animals (n=23, Pn=29, Pn=27, Pn=16, Pn=6, Pt½β=27 W0.26 in herbivorous animals and t½β=125 W0.32 in non‐herbivorous animals except pigs.Keywords
This publication has 0 references indexed in Scilit: