Anorexia of infection as a mechanism of host defense
Open Access
- 1 March 1979
- journal article
- research article
- Published by Elsevier in The American Journal of Clinical Nutrition
- Vol. 32 (3) , 593-596
- https://doi.org/10.1093/ajcn/32.3.593
Abstract
The role of anorexia of infection as a mechanism of host defense was studied by force-feeding infected mice to a normal energy intake. Their mortality and survival times were then compared with those of infected mice feeding ad libitum. Mortality was increased and survival time shortened in force fed animals. Our observations suggest that anorexia, by reducing energy intake, has a significant role in the early defense of the host.This publication has 3 references indexed in Scilit:
- STARVATION SUPPRESSION AND REFEEDING ACTIVATION OF INFECTIONThe Lancet, 1977
- Anorexia-producing intermediary metabolitesThe American Journal of Clinical Nutrition, 1976
- Metabolism Studies on the Brucella Group: III. Viability in Aqueous SolutionsThe Journal of Infectious Diseases, 1932