The Replacement of Cardiac Valves

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Abstract
This issue of the Journal contains a detailed review by Cohn et al. of a group of patients who underwent porcine bioprosthetic heart-valve replacement. Is the authors' final sentence ("Even with the uncertainty of long-term durability, if the risk of anticoagulation in an individual patient is high, tissue valves should be used.") supported by their data and by that in the literature?There is general agreement with their conclusions that the clinical improvement and actuarial survival rates of patients receiving porcine tissue valves (bioprostheses) are similar to those of patients receiving the available mechanical forms of prosthesis.1 , 2 Thromboembolism in the . . .

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