• 1 January 1977
    • journal article
    • research article
    • Vol. 16  (3) , 226-229
Abstract
Aqueous humor formation (AHF), uveoscleral flow (U), gross outflow facility (Cg), true facility of outflow from the anterior chamber (Ct1), true facility of outflow from anterior chamber into the general circulation (Ct2) and the pressure sensitivity of AHF (pseudofacility; Cp8) were determined in cynomologus monkey [Macaca fascicularis] eyes which had undergone total iris removal or iris removal followed by ciliary muscle disinsertion. AHF was in the normal range in iridectomized-only eyes. AHF was present but reduced in disinserted eyes. U was markedly reduced and similar in both types of eyes. Cp8 was normal and Cg, Ct1, and Ct2 were low in disinserted eyes. Cg, Ct1, and Ct2 were nearly equal in the disinserted eyes, indicating that gross facility consisted almost entirely of pressure-dependent flow from anterior chamber into the general circulation, presumably via the conventional drainage routes.