The Impact of Nocturnal Symptoms Associated With Gastroesophageal Reflux Disease on Health-Related Quality of Life
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Open Access
- 8 January 2001
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of internal medicine (1960)
- Vol. 161 (1) , 45-52
- https://doi.org/10.1001/archinte.161.1.45
Abstract
GASTROESOPHAGEAL reflux disease (GERD) is a chronic gastrointestinal condition characterized by heartburn and regurgitation caused by the reflux of acidic gastric contents into the esophagus. At least 15% of adults in the United States report having heartburn once a week or more. Between 35% and 70% of those with heartburn seeking medical care demonstrate evidence of esophagitis based on endoscopy.1,2 Individuals with heartburn or regurgitation often present with additional symptoms associated with GERD, such as noncardiac chest pain, dysphagia, dyspepsia, and globus sensation.3 Approximately 78% of patients with chronic hoarseness and more than 80% of patients with asthma have symptoms that may be associated with GERD.4Keywords
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