Primary hyperhidrosis
- 1 April 2003
- journal article
- Published by Springer Nature in Clinical Autonomic Research
- Vol. 13 (2) , 96-98
- https://doi.org/10.1007/s10286-003-0082-x
Abstract
Primary hyperhidrosis is a neurogenic disorder of unknown cause characterized by excessive sweating in the palmar surface of the hands, armpits, groin and feet. In the course of a therapeutic trial for primary hyperhidrosis, 62 % of patients reported a positive family history. Examination of these pedigrees demonstrated a sibling recurrence risk of λs = 29–48 and an offspring recurrence risk of λo = 41–68 indicating that hyperhidrosis can be an inherited condition. The pattern of inheritance suggests an autosomal dominant mode of transmission with incomplete disease penetrance.Keywords
This publication has 0 references indexed in Scilit: