Synthesis of O-α-D-galactopyranosyl-(1→2)-O-α-D-glucopyranosyl-(1→1)-D-glycerol, a degradation product of the glycolipid from a pneumococcus
- 1 January 1966
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society C: Organic
- Vol. 5, 521-523
- https://doi.org/10.1039/j39660000521
Abstract
O-α-D-Galactopyranosyl-(1 → 2)-O-α-D-glucopyranosyl-(1 → 1)-D-glycerol has been synthesised by a Koenigs–Knorr reaction from 2-O-(2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl)-3,4,6-tri-O-acetyl-α-D-glucopyranosyl bromide and methylenebis-2-O-(3-O-benzyl-D-glycerol) followed by removal of protecting groups. The reaction using the corresponding β-chloride also yielded the desired product but in lower overall yield. The synthetic glycoside was identical with the galactosylglucosyglycerol isolated by degradation of the major glycolipid from a rough strain of Pneumococcus, Type I.Keywords
This publication has 0 references indexed in Scilit: