Swelling of Damaged Brain Tissue

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Abstract
The brain of the guinea pig was shown to increase about 4% in weight within 30 minutes after decapitation. Later the gain in weight continues at a very much slower rate for several hours. This increase in brain weight is presumably an effect of fluid absorption. The initial rapidity of this phenomenon appears not to have been fully appreciated previously. Implications of these findings in studies of volume and water content of brains removed at necropsy are discussed. Local injury to .cerebral tissue is mentioned as a possible factor in the formation of cerebral edema in vivo.

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