Influence of 5-Fluorodeoxyuridine on Growth Characteristics of Rubella Virus.
- 1 November 1964
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 117 (2) , 410-413
- https://doi.org/10.3181/00379727-117-29595
Abstract
Summary Rubella virus grows to a maximum titer of approximately 10-5.0 Int.D.50 in LLC-MK2 cell cultures, with 2:1 input in50 multiplicity. There is always cell-associated virus which accounts for a small portion of the infectious yield. 5-FUDR did not affect in any way the yield of rubella virus as compared to the untreated control. Rubella virus therefore appears to belong to the RNA viruses. The authors are indebted to the Cancer Chemotherapy Service Center for 5-FUDR. The technical assistance of Miss Patricia Gosnell is gratefully acknowledged.Keywords
This publication has 3 references indexed in Scilit:
- Isolation in Tissue Culture of an Interfering Agent from Patients with Rubella.Experimental Biology and Medicine, 1962
- GROWTH CHARACTERISTICS OF MONKEY KIDNEY CELL STRAINS LLC-MK1, LLC-MK2, AND LLC-MK2(NCTC-3196) AND THEIR UTILITY IN VIRUS RESEARCHThe Journal of Experimental Medicine, 1962
- THE MODE OF ACTION OF 5-FLUOROURACIL AND ITS DERIVATIVESProceedings of the National Academy of Sciences, 1958