Abstract
Kangaroo rats were observed to be more active when fed only dry grain than when given succulents in their diet (Schmidt-Nielsen and Schmidt-Nielsen, 1952). This poses the question as to whether or not the activity of these animals is based on an unknown physiological regulatory mechanism. If such a mechanism exists, it may bring about an increase in activity of a water-deficient animal as a means of increasing its metabolic rate with a consequent increase in the formation of metabolic water. Conversely, augmentation of oxidation water would supposedly not be necessary if the animal had access to sufficient water in its diet.