Loss of Fertilizing Power of Sea-Urchin and Urechis Sperm Treated with "Univalent" Antibodies vs. Antifertilizin.
- 1 June 1946
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 62 (2) , 197-199
- https://doi.org/10.3181/00379727-62-15419
Abstract
Anti-sera were produced in rabbits by immunization with purified antifertilizin of Lytechinus and of Urechis and were photo-oxidized so as to convert the antibodies into the "univalent" (non-agglutinating) form. Sperm treated with such anti-sera were found to possess less than 1/64 of the fertilizing capacity of the controls although their activity was not noticeably affected. The bearing of the results on the significance of antifertilizin in the fertilization reaction is briefly discussed and the possible general use of "univalent" antibodies is mentioned.Keywords
This publication has 4 references indexed in Scilit:
- A Complement-Release Reaction; The Neutralization of the Anticomplementary Action of Sea-Urchin Fertilizin by AntifertilizinProceedings of the National Academy of Sciences, 1942
- THE ROLE OF ANTIFERTILIZIN IN THE FERTILIZATION OF SEA-URCHIN EGGSThe Biological Bulletin, 1941
- Extraction of an Egg-Membrane-Lysin from Sperm of the Giant Keyhole Limpet (Megathura Crenulata)Proceedings of the National Academy of Sciences, 1939
- SOME PROPERTIES OF SPERM EXTRACTS AND THEIR RELATIONSHIP TO THE FERTILIZATION REACTION IN ARBACIA PUNCTULATAThe Biological Bulletin, 1939