Biochemical adaptation as a response to exercise. 2. Adenosine triphosphatase and creatine phosphokinase activity in muscles of exercised rats

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Abstract
Male Wistar rats, 8 weeks old, were exercised by swimming for 30 min. daily for six 5-day weeks. The control animals were placed in the tank for 20 sec. daily to accustom them to the water. Adenosine triphosphatase and creatine phosphokinase were assayed in the muscles of the trained animals and their controls, both at rest and immediately after swimming for 5 min. Adenosine triphosphatase was also determined after a 30 min. swim. Neither the total activity of the 2 enzymes nor the activity measured in the absence of added Ca was affected by either the training or short-exercise procedures. The dry weight, total N and noncollagen N contents of the muscle were similarly unaffected by either the training or short exercise.