Immunity to mycobacteria: possible role of alpha/beta and gamma/delta T lymphocytes
- 1 July 1990
- Vol. 98 (7-12) , 669-673
- https://doi.org/10.1111/j.1699-0463.1990.tb04987.x
Abstract
Immunity to pathogenic mycobacteria is mediated by T lymphocytes. The possible contribution of CD4 alpha/beta T cells, CD8 alpha/beta T cells and gamma/delta T cells as well as the possible role of inter‐leukin‐mediated macrophage activation and target cell lysis through direct cell contact is discussed. Furthermore, attempts to define mycobacterial antigens for T lymphocytes with particular emphasis on heat shock proteins are described. The data currently available suggest complex interactions between different T‐cell types in immunity to mycobacteria.Keywords
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