The regulatory switch of the muscle thin filament: Ca2+ or myosin heads?
- 1 June 1994
- journal article
- review article
- Published by Springer Nature in Journal of Muscle Research and Cell Motility
- Vol. 15 (3) , 232-236
- https://doi.org/10.1007/bf00123476
Abstract
Ca2+ and myosin heads are both involved in regulation, with Ca2+ as the allosteric trigger and the myosin head-induced Tm off-on transition as the switch. The allosteric/cooperative model is a good phenomenological description of part of the process and aspects of the original steric blocking model are involved in the molecular mechanisms.Keywords
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