A convenient synthesis of 4-hydroxyoestradiol triacetate [oestra-1,3,5(10)-triene-3,4,17β-triol triacetate]

Abstract
4-Hydroxyoestradiol triacetate is easily prepared from the 4-acetoxymercurio derivative of oestradiol by using lead tetra-acetate in a metal–metal exchange reaction to introduce the oxygen substituent at C-4.

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