NEW SYNTHESIS OF (±)-SEMPERVIROL

Abstract
The new synthesis of (±)-sempervirol (I) was described. Condensation of β-cyclocitral (II) with 4-isopropyl-3-methoxybenzyl chloride (XII) gave an alcohol (XIII), which by oxidation and subsequent intramolecular cyclization gave trans- and cis-fused 6-oxo compounds (XV and XVI). Both XV and XVI were respectively converted into (±)-I.

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