Branching of Ketosugars by Ethyl Trimethylsilyl-Acetate/Tetra-n-Butylammonium Fluoride

Abstract
Hexopyranose- and hexofuranose-uloses, on treatment with ethyl trirnethylsilylacetate/tetra-n-butylammohium fluoride, form β-hydroxy esters or derivatives thereof instead of their TMS-enol ethers. 29Si NMR studies confirm the proposed mechanism.