Muscarinic agonist SAR of azaspirodioxolanes
- 1 August 1992
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 2 (8) , 815-820
- https://doi.org/10.1016/s0960-894x(00)80537-5
Abstract
No abstract availableKeywords
This publication has 8 references indexed in Scilit:
- Synthesis and in vitro biological profile of all four isomers of the potent muscarinic agonist 3-(3-methyl-1,2,4-oxadiazol-5-yl)-1-azabicyclo[2.2.1]heptaneJournal of Medicinal Chemistry, 1992
- Muscarinic activity of the thiolactone, lactam, lactol, and thiolactol analogs of pilocarpine and a hypothetical model for the binding of agonists to the M1 receptorJournal of Medicinal Chemistry, 1992
- 2-Methyl-1,3-dioxaazaspiro[4.5]decanes as novel muscarinic cholinergic agonistsJournal of Medicinal Chemistry, 1988
- Synthesis and characterization of all four isomers of the muscarinic agonist, 2'-methylspiro[1-azabicyclo[2.2.2]octane-3,4'-[1,3]dioxolane]Journal of Medicinal Chemistry, 1987
- Molecular requirements of the recognition site of cholinergic receptors. 22. Resolution, absolute configuration, and cholinergic enantioselectivity of (+)- and (-)-cis-2-methyl-5-[(dimethylamino)methyl]-1,3-oxathiolane methiodideJournal of Medicinal Chemistry, 1986
- The pharmacological assessment of RS 86 (2-ethyl-8-methyl-2,8-diazaspiro-[4,5]-decan-1,3-dion hydrobromide). A potent, specific muscarinic acetylcholine receptor agonistEuropean Journal of Pharmacology, 1986
- Stereochemistry of the Interaction of Enantiometic 1,3-Dioxolane Analogs of Muscarone with Cholinergic Receptors1Journal of Medicinal Chemistry, 1963
- STUDIES ON THE CHEMICAL BASIS FOR CHOLINOMIMETIC AND CHOLINOLYTIC ACTIVITY: PART I. THE SYNTHESIS AND CONFIGURATION OF QUATERNARY SALTS IN THE 1,3-DIOXOLANE AND OXAZOLINE SERIESCanadian Journal of Chemistry, 1962