Histone dimers: a fundamental unit in histone assembly
Open Access
- 1 May 1976
- journal article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 3 (5) , 1263-1276
- https://doi.org/10.1093/nar/3.5.1263
Abstract
Histone interactions which occur, at moderate ionic strengths, when several types of purified, renatured histones are mixed at equimolar ratios have been studied. The four histones H2A,H2B,H3 and H4 complex and form dimers. Histone H1 does not interact with the other four histone types and does not form dimers. Mixing of single histone species with preformed histone pairs as well as mixing of two different types of histone pairs, leads to exchange of histones among the pairs and formation of dimers. No trimers are formed. The dimers are in equilibrium with high-molecular weight histone structures.Keywords
This publication has 25 references indexed in Scilit:
- Dynamic equilibrium in histone assembly. Self-assembly of single histones and histone pairsBiochemistry, 1975
- Covalent cross‐linking of histones in chromatinFEBS Letters, 1975
- Histone cross-complexing patternBiochemistry, 1974
- Interactions of histone LAK (f2a2) with histones KAS (f2b) and GRK (f2a1)Biochemistry, 1974
- Isolation of a histone IIb1–IIb2 complexBiochemical and Biophysical Research Communications, 1973
- Purification of the five main calf thymus histone fractions by gel exclusion chromatographyFEBS Letters, 1973
- The structure of partially histone depleted nucleohistoneFEBS Letters, 1973
- A super-coil model for nucleohistoneJournal of Molecular Biology, 1972
- Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Nature, 1970
- The molecular weight of lysine-rich histoneBiochemical and Biophysical Research Communications, 1965