The contribution of HPV18 to cervical cancer is underestimated using high-grade CIN as a measure of screening efficiency
Open Access
- 20 March 2007
- journal article
- research article
- Published by Springer Nature in British Journal of Cancer
- Vol. 96 (8) , 1234-1236
- https://doi.org/10.1038/sj.bjc.6603693
Abstract
In one geographical area, 14 high-risk human papillomavirus types in cervical intraepithelial neoplasia (CIN2/3; n=139) and cervical squamous cell carcinoma (SCC; n=84) were analysed. HPV18 was more prevalent in SCC than CIN2/3 (OR 9.8; 95% confidence interval: 2.5–39). Other high-risk types prevalences corresponded in CIN2/3 and SCC. Evaluations using CIN2/3 as a measure of efficiency underestimate the contribution of HPV18 to SCC.Keywords
This publication has 32 references indexed in Scilit:
- Estimating species richness by a Poisson-compound gamma modelBiometrika, 2010
- Modeling interactions between adjacent nucleosomes improves genome-wide predictions of nucleosome occupancyBioinformatics, 2009
- The DNA-encoded nucleosome organization of a eukaryotic genomeNature, 2008
- Dynamic Regulation of Nucleosome Positioning in the Human GenomeCell, 2008
- A high-resolution atlas of nucleosome occupancy in yeastNature Genetics, 2007
- The Elevated 10-Year Risk of Cervical Precancer and Cancer in Women With Human Papillomavirus (HPV) Type 16 or 18 and the Possible Utility of Type-Specific HPV Testing in Clinical PracticeJNCI Journal of the National Cancer Institute, 2005
- Human Papillomavirus Type 16 Infections and 2-Year Absolute Risk of Cervical Precancer in Women With Equivocal or Mild Cytologic AbnormalitiesJNCI Journal of the National Cancer Institute, 2005
- Evidence for nucleosome depletion at active regulatory regions genome-wideNature Genetics, 2004
- Comparison of HPV type distribution in high-grade cervical lesions and cervical cancer: a meta-analysisBritish Journal of Cancer, 2003
- Epidemiologic Classification of Human Papillomavirus Types Associated with Cervical CancerNew England Journal of Medicine, 2003