Healing and Recurrence of Duodenal Ulcers in Relation to the Acid-Secreting Area

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Abstract
The relation of the gastric acid-secreting area to the healing and recurrence of duodenal ulcers was examined in 67 patients with duodenal ulcers. Studies were made by the endoscopic Congo red test. A close correlation between the healing and recurrence of duodenal ulcers and the extent of the acid-secreting area was indicated. When the acid-secreting area was large, the ulcers did not heal satisfactorily within 4 wk after initiation of medical treatment and frequently recurred. When the acid-secreting area was small, the ulcers tended to heal rapidly and not to recur.