Effects of Urea Treatment in Malignancies of the Conjunctiva and Cornea (with 1 colour plate)

Abstract
A series of 9 patients with extensive squamous cell carcinomas of the conjunctiva, affecting also the cornea in 5 of them, were treated with local applications of urea. Of these patients, 8 were cured. In 1 patient with a concomitant extensive conjunctivitis, the treatment was ineffective. Urea treatment is very simple and without any complications, apart from a transient opacity of the cornea. Recurrences are easily and effectively retreated as in 1 of 2 of our cases. But if the eyeball has been destroyed, as in the 2nd case, retreatment is impossible. At least 5 of the treated patients would have had an enucleation of the globe or an exenteration of the orbit without the urea treatment.

This publication has 1 reference indexed in Scilit: