SCLEROSING cholangitis is a rare cause of extrahepatic obstructive jaundice. The disease results from diffuse inflammation and fibrosis of the submucosal and subserosal layers of the extrahepatic biliary tree wall with consequent progressive obliteration of the lumen. Regional enteritis, which has been found in association with fibrous retroperitonitis, is reported here for the first time, as far as we know, in association with sclerosing cholangitis. Report of a Case A white woman born in 1915 stated that she had "colitis" when she was 19 years old. She gave birth to a normal child in 1951. Following childbirth she had intermittent diarrhea for three years. In 1954, at the time she was having severe diarrhea, a diagnosis of regional ileitis was made by roentgen examination. The terminal ileum was narrowed and the loop proximal to this was dilated. The erythrocyte sedimentation rate (ESR) was 36 mm in one hour by the