Antimicrobial Susceptibility among Pathogens Collected from Hospitalized Patients in the United States and In Vitro Activity of Tigecycline, a New Glycylcycline Antimicrobial

1 October 2006

journal article
Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy

Vol. 50 (10) , 3479-3484
https://doi.org/10.1128/aac.00210-06

Abstract

The activities of tigecycline and comparators against isolates collected from 76 U.S. centers between January 2004 and September 2005 were assessed. Tigecycline MIC(90)s were < or =2 microg/ml for Klebsiella pneumoniae, Klebsiella oxytoca, Escherichia coli, Enterobacter aerogenes, Enterobacter cloacae, Serratia marcescens, Acinetobacter baumannii, Staphylococcus aureus, Enterococcus faecalis, Enterococcus faecium, and Streptococcus agalactiae.

Keywords

This publication has 16 references indexed in Scilit:

Clinical impact and pathogenicity of Acinetobacter
Clinical Microbiology & Infection, 2005
Overview of Nosocomial Infections Caused by Gram-Negative Bacilli
Clinical Infectious Diseases, 2005
In Vitro Activity of Tigecycline against Isolates from Patients Enrolled in Phase 3 Clinical Trials of Treatment for Complicated Skin and Skin‐Structure Infections and Complicated Intra‐Abdominal Infections
Clinical Infectious Diseases, 2005
The Efficacy and Safety of Tigecycline for the Treatment of Complicated Intra‐Abdominal Infections: Analysis of Pooled Clinical Trial Data
Clinical Infectious Diseases, 2005
BK Virus: Opportunity Makes a Pathogen
Clinical Infectious Diseases, 2005
Antimicrobial activity of tigecycline tested against nosocomial bacterial pathogens from patients hospitalized in the intensive care unit
Diagnostic Microbiology and Infectious Disease, 2005
MRSA – what is it, and how do we deal with the problem?
Emerging Therapeutic Targets, 2005
In vitro susceptibilities of aerobic and facultative Gram-negative bacilli isolated from patients with intra-abdominal infections worldwide: the 2003 Study for Monitoring Antimicrobial Resistance Trends (SMART)
Journal of Antimicrobial Chemotherapy, 2005
Occurrence and antimicrobial resistance pattern comparisons among bloodstream infection isolates from the SENTRY Antimicrobial Surveillance Program (1997–2002)
Diagnostic Microbiology and Infectious Disease, 2004
Assessment of pathogen occurrences and resistance profiles among infected patients in the intensive care unit: report from the SENTRY Antimicrobial Surveillance Program (North America, 2001)
International Journal of Antimicrobial Agents, 2004