Genetic Mapping of the Inversion Loop in Bacteriophage Mu DNA
- 1 July 1973
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 70 (7) , 2153-2156
- https://doi.org/10.1073/pnas.70.7.2153
Abstract
An inversion loop seen in heteroduplex mapping of the DNA of mature Mu phage induced from a lysogen is observed also in defective lambda phage carrying one end of Mu. 14% of the DNA of Mu, including this region, designated the G loop, is shown to be to the right of all known genes in the prophage map. The inhomogeneous ends of Mu are observed as a separate phenomenon and appear in all mutants investigated. The recA and recBC functions of the host are not needed for the inversion responsible for the G loop to take place. Deletions of Mu DNA in the G-loop region have been isolated and are under study.Keywords
This publication has 4 references indexed in Scilit:
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- Structure of Inserted Bacteriophage Mu-1 DNA and Physical Mapping of Bacterial Genes by Mu-1 DNA InsertionProceedings of the National Academy of Sciences, 1972
- Bacteriophage Mu integration: On the mechanism of Mu-induced mutationsJournal of Molecular Biology, 1971
- Deletion mutants of bacteriophage lambdaJournal of Molecular Biology, 1971