Epidural Morphine for Postoperative Analgesia

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Abstract
Of morphine intramuscularly, or saline epidurally at the end of surgery. Following epidural morphine, postoperative pain was less frequent, less intense and of shorter duration, use of analgesics and sedative was less frequent; and the postoperative feeling of well-being was rated better than after systemic morphine or epidural saline. These effects were more frequent when bupivacaine was used for operative epidural anesthesia than when mepivacaine was used. The results were age independent. Side effects following epidural morphine included pruritus and disturbances of micturition. Nausea, vomiting, fatigue, and headache were of comparable frequency in the three groups. Results of this study were evaluated in the doctoral dissertation of W. Riess. Reprint requests to Dr. Lanz. Accepted for publication October 27,1981. © 1982 International Anesthesia Research Society...

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