Solution solution: using NMR models for molecular replacement
Open Access
- 21 September 2001
- journal article
- review article
- Published by International Union of Crystallography (IUCr) in Acta Crystallographica Section D-Biological Crystallography
- Vol. 57 (10) , 1457-1461
- https://doi.org/10.1107/s0907444901010824
Abstract
NMR structures can serve as a good source of search models in crystal structure determination by molecular replacement. However, owing to the inherent problems of NMR models, this procedure is not always straightforward. Here, an updated overview is presented with particular emphasis on the preparation of NMR search models and the latest trends in methodology. An experimental protocol developed recently is described and results on its use in solving a new structure as well as its test against a difficult published case are presented.Keywords
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