Localization of the human fibronectin (FN) gene on chromosome 8 by a specific enzyme immunoassay
- 1 June 1981
- journal article
- research article
- Published by Springer Nature in Biochemical Genetics
- Vol. 19 (5-6) , 551-566
- https://doi.org/10.1007/bf00484626
Abstract
The fibronectin produced by clonal murine-human hybrid cell lines containing various complements of human chromosomes was measured. Human and murine fibronectins were assayed by specific immunoassay, and the production of human fibronectin was correlated with karyology and isozyme markers for specific human chromosomes. The data show a 100% concordance between the expression of human fibronectin and glutathione reductase, a marker for human chromosome 8, indicating that chromosome 8 codes for the fibronectin polypeptide.Keywords
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