The Antigenic Role of the Excretions and Secretions of Adult Trichinella spiralis in the Production of Immunity in Mice
- 1 December 1957
- journal article
- research article
- Published by JSTOR in Journal of Parasitology
- Vol. 43 (6) , 593-598
- https://doi.org/10.2307/3286546
Abstract
Antigenic material associated with the excretions and secretions of adult T. spiralis was collected by incubating the worms in a nutrient fluid for 2 days. When used unaltered and given in small daily injections, it produced an immunity in mice as revealed after certain infections by the presence of significantly smaller worm burdens (adults and larvae) than those in controls. Twelve injections were required to demonstrate a reduction in the number of adult worms, whereas a reduction in the number of larvae was noted after both 6 and 12 injections. The results show that the adult phase of T. spiralis, as well as the pre-adult phase reported earlier, contributes to the total immunity produced by the host.Keywords
This publication has 1 reference indexed in Scilit:
- The Antigenic Role of the Excretions and Secretions of Trichinella spiralis in the Production of Immunity in MiceJournal of Parasitology, 1955