Occupational Acroosteolysis

Abstract
An Industrial hygiene survey was conducted in respect to occupational acroosteolysis (AOL) in 32 plants engaged in production and compounding of polyvinyl chloride. This survey was limited to inspection of facilities, interrogation of technical personnel, and statistical analyses. All manufacturing processes and chemicals utilized were explored. A major objective was the identification of variables in processes and chemicals that were peculiar to those plants affording known cases of AOL. No such processes or chemicals were found. The survey brought to light a number of situations suspected of relationship to the precise cause of AOL, some of which require additional exploration. Most positive of these was the finding that essentially all of the persons who developed AOL had served as reactor cleaners using manual methods.

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