Tizanidine and spasticity

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Abstract
To the Editor: Presentation of the problem. The Role of tizanidine in the treatment of spasticity, the recent 80-page supplement to Neurology [1] subsidized by the manufacturer of tizanidine, sets me up front [2] as the stalking horse entree of the symposium. Of course, I was flattered to gain the editor's attention to my ancient essay [3]: ``he [Landau] considered destruction of parts of the segmental stretch reflex arc to be the most reasonable therapeutic approach to the treatment of spasticity.'' Not so. (Later in his own review, [4] Young more accurately indicates that I was referring only to the disabling positive symptom of flexor spasms in patients who are already paraplegic.) But whether my old ``hypothesis [actually current data, argument, and inference] was inaccurate'' is a trivial issue. What is the evidence that tizanidine pills are indeed a great remedy for the concrete disabilities of afflicted patients?

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