HT29‐MTX and Caco‐2/TC7 Monolayers as Predictive Models for Human Intestinal Absorption: Role of the Mucus Layer
- 1 October 2001
- journal article
- research article
- Published by Elsevier in Journal of Pharmaceutical Sciences
- Vol. 90 (10) , 1608-1619
- https://doi.org/10.1002/jps.1111
Abstract
No abstract availableKeywords
This publication has 23 references indexed in Scilit:
- Role of P‐glycoprotein‐mediated secretion in absorptive drug permeabiity: An approach using passive membrane permeability and affinity to P‐glycoprotein††Dedicated to Prof. B. C. Lippold on the occasion of his 60th birthday.Journal of Pharmaceutical Sciences, 1999
- Diffusion of Drugs in Native and Purified Gastrointestinal MucusJournal of Pharmaceutical Sciences, 1997
- Caco-2 monolayers in experimental and theoretical predictions of drug transportAdvanced Drug Delivery Reviews, 1996
- Characterisation of a newly isolated Caco-2 clone (TC-7), as a model of transport processes and biotransformation of drugsInternational Journal of Pharmaceutics, 1995
- The mucus layer as a barrier to drug absorption in monolayers of human intestinal epithelial HT29-H goblet cellsInternational Journal of Pharmaceutics, 1993
- Adaptation to 5‐fluorouracil of the heterogeneous human colon tumor cell line ht‐29 results in the selection of cells committed to differentiationInternational Journal of Cancer, 1991
- Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cellsBiochemical and Biophysical Research Communications, 1991
- Characteristics of Sodium Flux from Serosa to Mucosa in Rabbit IleumThe Journal of general physiology, 1974
- Ionic Conductances of Extracellular Shunt Pathway in Rabbit IleumThe Journal of general physiology, 1972
- Histological Demonstration of Mucin after Periodic AcidNature, 1946