Cobalt(III) complexes with thiosemicarbazones as co-ordinating agents. Spontaneous resolution by crystallization and absolute configuration
- 1 January 1995
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in J. Chem. Soc., Dalton Trans.
- No. 18,p. 3035-3040
- https://doi.org/10.1039/dt9950003035
Abstract
Two new cobalt(III) complexes with pyridoxal [3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde] and pyruvic acid thiosemicarbazones (H2L and H2pt)[Co(HL)2]Cl·EtOH 1 and [Co(Hpt)(pt)]2 respectively, have been synthesized and characterized using single-crystal X-ray diffraction and IR and CD spectroscopic methods. The structure of 2-thio-6-azathymine [6-methyl-3-thioxo-1,2,4-triazin-5-(2H,4H)-one] obtained upon cyclization of methyl pyruvate thiosemicarbazone in the course of its complexation reaction with cobalt(II) salts is also described. The structure of 1 consists of discrete [Co(HL)2]+ cations, Cl– anions and ethanol solvate molecules, that of 2 consists of neutral monomers and the two ligands are not equivalent. In both complexes the co-ordination geometry about cobalt is distorted octahedral and the two ligands are in the mer configuration (S and O atoms cis to each other and the N atoms trans). Complex 1, an example of optical resolution by preferential crystallization, is chiral.Keywords
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