Invasive Pneumococcal Disease Among Infants Before and After Introduction of Pneumococcal Conjugate Vaccine
Top Cited Papers
Open Access
- 12 April 2006
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 295 (14) , 1668-1674
- https://doi.org/10.1001/jama.295.14.1668
Abstract
Streptococcus pneumoniae causes invasive diseases such as meningitis, bacteremia, and pneumonia in children. A heptavalent pneumococcal conjugate vaccine (PCV7) was licensed in February 2000 and recommended for all children aged 2 to 23 months in the United States.1,2 Since PCV7 introduction, the rate of invasive pneumococcal disease (IPD) among US children younger than 2 years has decreased by at least 60%.3,4 Concurrently, rates of IPD in adults have decreased.3,4 These declines suggest that PCV7 vaccination of children aged 2 to 23 months has led to changes in pneumococcal carriage in both the target and nontarget populations.Keywords
This publication has 0 references indexed in Scilit: