Quantitation of proinsulin mRNA sequences in hamster insulinoma cells in culture by molecular hybridization
- 1 February 1980
- journal article
- specialia
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 36 (2) , 187-188
- https://doi.org/10.1007/bf01953722
Abstract
Summary The content of proinsulin mRNA sequences was measured in a cultured cell line established from a transplantable hamster islet cell tumor, by hybridization with proinsulin cDNA. The cells cultured in vitro were found to contain a significant amount of proinsulin mRNA sequences, compared with non-insulin-producing hamster tissues, and seem to be a useful system for the study of insulin gene expression.Keywords
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