Passage of Selenium across the Placenta and also into the Milk of the Dog
- 1 December 1964
- journal article
- research article
- Published by Elsevier in Journal of Nutrition
- Vol. 84 (4) , 340-344
- https://doi.org/10.1093/jn/84.4.340
Abstract
After a single, subtoxic, subcutaneous injection of radioactive selenium, as selenious acid, selenium passed through the mammary glands into the milk of the dog. The administered inorganic selenium was converted into organoselenium in the milk, because nearly all the Se75 was present in the proteins of the milk. It was observed that selenium was distributed equally between casein and milk serum proteins. At the time of the second pregnancy, the radioactive isotope was still detectable in the bitch and appeared in the milk when lactation began after the second pregnancy. Selenium-75 was transported across the placental membrane, since it was observed in the pups delivered by Caesarean section.Keywords
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