Effect of Malnutrition During Pregnancy on the Development of the Mammary Glands of Rats
- 1 November 1981
- journal article
- research article
- Published by Elsevier in Journal of Nutrition
- Vol. 111 (11) , 1937-1941
- https://doi.org/10.1093/jn/111.11.1937
Abstract
Sprague-Dawley rats fed 50% of normal food intake from day 5 of gestation had a marked reduction in the weight of their left mammary glands compared with control nonrestricted animals. The affected glands had a significant reduction in DNA, RNA and protein content. Protein/DNA ratio was also reduced while RNA/DNA ratio was unchanged. Histological studies of the glands revealed a reduced number of parenchymal cells, reduced cell size and larger lumen within the alveoli.Keywords
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