Amino acid sequence of ATP phosphoribosyltransferase of Salmonella typhimurium.
- 1 April 1979
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 76 (4) , 1589-1592
- https://doi.org/10.1073/pnas.76.4.1589
Abstract
The amino acid sequence of ATP phosphoribosyltransferase [1-(5'-phosphoribosyl)-ATP:pyrophosphate phosphoribosyltransferase, EC 2.4.2.17] of Salmonella typhimurium has been determined. The amino acid sequence analysis was carried out with a combination of manual and automated methods. It was complemented by DNA sequence analysis (done in another laboratory) of the hisG gene, which codes for it. The subunit polypeptide chain contains 299 amino acid residues and has a molecular weight of 33,216. The amino-terminal segment of the protein is relatively basic in character and has limited sequence homologies with the lac repressor and histidinol dehydrogenase. In addition, the protein contains a 40-residue segment that has 13 residues identical with the sequence surrounding the active-site cysteine of glyceraldehyde-3-phosphate dehydrogenase.This publication has 31 references indexed in Scilit:
- DNA sequence from the histidine operon control region: seven histidine codons in a row.Proceedings of the National Academy of Sciences, 1978
- Nucleotide sequence of the attenuator region of the histidine operon of Escherichia coli K-12.Proceedings of the National Academy of Sciences, 1978
- [21] Cleavage at glutamic acid with staphylococcal proteasePublished by Elsevier ,1977
- Specific binding of the first enzyme for histidine biosynthesis to the DNA of the histidine operonNucleic Acids Research, 1975
- AUTOREGULATION OF GENE EXPRESSIONAnnual Review of Microbiology, 1975
- A Rapid Isolation of Phosphoribosyladenosine Triphosphate Synthetase and Comparison to Native EnzymeJournal of Biological Chemistry, 1974
- The Amino-Acid Sequence of lac RepressorProceedings of the National Academy of Sciences, 1973
- Thin-layer chromatography of sub-nanomole amounts of phenylthiohydantoin (PTH) amino acids on polyamide sheetsAnalytical Biochemistry, 1973
- Amino-acid Sequence of Glyceraldehyde 3-Phosphate Dehydrogenase from Lobster MuscleNature, 1967
- Purification and Composition Studies of Phosphoribosyl-adenosine Triphosphate: Pyrophosphate Phosphoribosyltransferase, the First Enzyme of Histidine BiosynthesisJournal of Biological Chemistry, 1967