X–chromosome inactivation during differentiation of female teratocarcinoma stem cells in vitro

1 January 1978

journal article
research article
Published by Springer Nature in Nature

Vol. 271 (5643) , 329-333
https://doi.org/10.1038/271329a0

Abstract

Evidence is presented that both X chromosomes are genetically active in clonal cultures of undifferentiated female mouse teratocarcinoma stem cells derived from a spontaneous ovarian tumour. As the cells differentiate in vitro one of the X chromosomes becomes inactivated.

Keywords

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