Successful Treatment of Post‐Transfusion Purpura with High Dose Immunoglobulins after Lack of Response to Plasma Exchange
- 1 August 1985
- journal article
- case report
- Published by Wiley in Vox Sanguinis
- Vol. 49 (2) , 164-167
- https://doi.org/10.1111/j.1423-0410.1985.tb00786.x
Abstract
A 77-year-old woman with post-transfusion purpura failed to respond to two 2.5-litre plasma exchanges with albumin as a replacement fluid. However, intravenous infusion of high-dose human immunoglobulin produced a response within 4 h. It is suggested that plasma exchange and exchange transfusion are effective in this condition mainly because they have allowed large doses of immunoglobulin to be infused in the form of plasma or whole blood.Keywords
This publication has 14 references indexed in Scilit:
- ANTI-IDIOTYPIC SUPPRESSION OF AUTOANTIBODIES TO FACTOR VIII (ANTIHAEMOPHILIC FACTOR) BY HIGH-DOSE INTRAVENOUS GAMMAGLOBULINThe Lancet, 1984
- High-Dose Intravenous Immunoglobulin for Post-Transfusion PurpuraNew England Journal of Medicine, 1983
- Monomeric IgG preparations for intravenous use inhibit platelet stimulation by polymeric IgGBritish Journal of Haematology, 1983
- Transient Reversal of Thrombocytopenia in Idiopathic Thrombocytopenic Purpura by High-Dose Intravenous Gamma GlobulinNew England Journal of Medicine, 1982
- Post-transfusion purpura: response to steroids and association with red blood cell and lymphocytotoxic antibodiesBritish Journal of Haematology, 1982
- Post‐transfusion Purpura: a Serological and Immunochemical StudyBritish Journal of Haematology, 1981
- Post‐transfusion purpura: An enigma of alloimmunizationAmerican Journal of Hematology, 1980
- Post‐Transfusion Purpura Treated with Plasma Exchange by Haemonetics Cell SeparatorActa Medica Scandinavica, 1978
- Post-Transfusion Purpura: Immunologic Aspects and TherapyNew England Journal of Medicine, 1974
- IMMUNOREACTIONS INVOLVING PLATELETS. V. POST-TRANSFUSION PURPURA DUE TO A COMPLEMENT-FIXING ANTIBODY AGAINST A GENETICALLY CONTROLLED PLATELET ANTIGEN. A PROPOSED MECHANISM FOR THROMBOCYTOPENIA AND ITS RELEVANCE IN “AUTOIMMUNITY”*Journal of Clinical Investigation, 1961