Whole-Brain Radiotherapy in the Management of Brain Metastasis
Top Cited Papers
- 10 March 2006
- journal article
- review article
- Published by American Society of Clinical Oncology (ASCO) in Journal of Clinical Oncology
- Vol. 24 (8) , 1295-1304
- https://doi.org/10.1200/jco.2005.04.6185
Abstract
Brain metastases are an important cause of morbidity and mortality, afflicting nearly 170,000 Americans annually. The prognosis for these patients is poor, with median survival times measured in months. In this review article, we present the standard treatment approach of whole-brain radiotherapy and discuss new directions, including the role of chemical modifiers and the management and prevention of neurocognitive deficits.Keywords
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