Preparation of 2-Thiazolines from (1,2)-Thioamido-Alcohols; DAST as a Useful Reagent
- 1 February 1995
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1995 (02) , 171-172
- https://doi.org/10.1055/s-1995-4886
Abstract
Diethylamidosulfur trifluoride (DAST) is shown to be a valuable reagent for the ready access to 2-thiazolines 4a-f starting from the corresponding (1,2)-thioamido-alcohols 3a-f. This mild intramolecular cyclization is fast (< 1 h) and occurs at a temperature as low as -78 °C.Keywords
This publication has 0 references indexed in Scilit: