Signaling mechanisms for regulation of chemotaxis
Open Access
- 1 January 2005
- journal article
- review article
- Published by Springer Nature in Cell Research
- Vol. 15 (1) , 52-56
- https://doi.org/10.1038/sj.cr.7290265
Abstract
Chemotaxis is a fascinating biological process, through which a cell migrates along a shallow chemoattractant gradient that is less than 5% difference between the anterior and posterior of the cell. Chemotaxis is composed of two independent, but interrelated processes-motility and directionality, both of which are regulated by extracellular stimuli, chemoattractants. In this mini-review, recent progresses in the understanding of the regulation of leukocyte chemotaxis by chemoattractant signaling are reviewed.Keywords
This publication has 56 references indexed in Scilit:
- Parsing the Polarity CodeNature Reviews Molecular Cell Biology, 2004
- Inflammation and cancerNature, 2002
- Inflammation in atherosclerosisNature, 2002
- Points of control in inflammationNature, 2002
- Tumor Suppressor PTEN Mediates Sensing of Chemoattractant GradientsCell, 2002
- Central Role for G Protein-Coupled Phosphoinositide 3-Kinase γ in InflammationScience, 2000
- Roles of PLC-β2 and -β3 and PI3Kγ in Chemoattractant-Mediated Signal TransductionScience, 2000
- αPix Stimulates p21-activated Kinase Activity through Exchange Factor-dependent and -independent MechanismsJournal of Biological Chemistry, 1999
- Inositol phospholipids: Translocation, translocation, translocation …Current Biology, 1998
- PTEN , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate CancerScience, 1997