Use of Antithrombin Concentrate in Stable Diffuse Intravascular Coagulation

Abstract
A 39-yr-old woman suffering from a myelodysplastic syndrome, who developed a moderately severe stable diffuse intravascular coagulation (DIC) during an uneventful pregnancy, was studied. I.v. administration of antithrombin III concentrate was attempted to combat the DIC. Improved survival of platelet transfusions, facilitating supportive care, suggested some therapeutic benefit. Only minimal effects on the results of the coagulation tests were observed.