jPHYDIT: a JAVA-based integrated environment for molecular phylogeny of ribosomal RNA sequences

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Abstract
Summary: jPHYDIT is a Java application designed to furnish a visual and integrated environment for molecular phylogeny. The program can be used to visualize intra-strand base-pairing information in secondary and tertiary structures of ribosomal RNA (rRNA) sequences. A function for the semi-automated alignment was included to facilitate handling of the database containing a large number of multiple-aligned rRNA sequences. Integration of nucleotide sequence editing, pairwise alignment, multiple alignment and phylogenetic treeing functions provide an easy and efficient way of analyzing rRNA sequences for molecular evolution, systematics, epidemiology and ecology. Availability: jPHYDIT is available freely over the Internet at http://chunlab.snu.ac.kr/jphydit/. The platform-independent JAVA technology provides distributions for various operating systems and hardware architectures. Contact:jchun@snu.ac.kr